MIR143HG
mir143hg: A Non-Coding RNA with Profound Impact on Health and Disease
Description
mir143hg is a long non-coding RNA (lncRNA) that plays a crucial role in various cellular processes. It is located within the MIR143/145 gene cluster on chromosome 5 and is characterized by its ability to regulate gene expression without being translated into protein.
Associated Diseases
Research has linked mir143hg to the development and progression of several diseases, including:
- Cancer: mir143hg has been found to be overexpressed in various cancer types, including lung, breast, colorectal, and liver cancer. It is believed to promote cancer cell growth, metastasis, and resistance to therapy.
- Cardiovascular disease: mir143hg has also been implicated in the development of cardiovascular diseases, such as atherosclerosis and coronary artery disease. It is thought to regulate genes involved in cholesterol metabolism and inflammation.
- Neurological disorders: Studies have shown that mir143hg levels are altered in individuals with neurological disorders such as Alzheimer's disease and schizophrenia. It may play a role in cognitive function and synaptic plasticity.
Did you Know ?
According to a recent study, patients with increased levels of mir143hg in their blood were more likely to develop lung cancer within the next 5 years. This finding suggests that mir143hg could potentially serve as an early detection marker for lung cancer.
