MIR106B
Description
The MIR106B (microRNA 106b) is a ncRNA gene located on chromosome 7.
miR-106b is a microRNA that is located on chromosome X. It is transcribed as a precursor molecule, which is then processed into a mature microRNA. miR-106b is highly conserved among vertebrates, suggesting that it plays an important role in cellular function.
miR-106b is a microRNA that is involved in the regulation of various cellular processes, including cell proliferation, apoptosis, and differentiation. It has been shown to play a role in cancer development and progression. For example, miR-106b is upregulated in various types of cancer, including lung cancer, breast cancer, and colorectal cancer, and its overexpression contributes to tumor growth and metastasis. In addition, miR-106b has been implicated in the regulation of the immune system. It has been shown to suppress the activity of immune cells, such as T cells and natural killer cells, which may contribute to immune evasion by cancer cells. miR-106b also targets and regulates genes involved in the apoptotic pathway, including the anti-apoptotic protein Bcl-2. By downregulating Bcl-2, miR-106b promotes apoptosis, which can be a mechanism for suppressing tumor growth. Furthermore, miR-106b is known to play a role in cellular differentiation. It has been shown to regulate the differentiation of various cell types, including neural cells, muscle cells, and bone cells. Overall, miR-106b is a versatile microRNA that plays a complex role in the regulation of various cellular processes.
MIR106B is also known as MIRN106B, mir-106b.
