Proteus mirabilis

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Proteus mirabilis: A Stealthy Pathogen with Surprising Consequences

Introduction

Proteus mirabilis, a Gram-negative bacterium, is a ubiquitous resident of the human microbiome. While it generally exists harmlessly, Proteus mirabilis can cause a range of infections, including urinary tract infections (UTIs) and sepsis.

Description

Proteus mirabilis is a motile, rod-shaped bacterium with a characteristic "swarming" behavior. This behavior allows it to spread rapidly across surfaces, forming a thin, veil-like biofilm. Proteus mirabilis also possesses fimbriae, hair-like structures that enable it to adhere to host cells.

Associated Diseases

Proteus mirabilis is primarily associated with the following infections:

• Urinary Tract Infections (UTIs): Proteus mirabilis is a common cause of UTIs, particularly in women. Its ability to form biofilms on catheters and other medical devices increases the risk of infection.
• Sepsis: In severe cases, Proteus mirabilis can enter the bloodstream and cause sepsis, a life-threatening condition.
• Pneumonia: Proteus mirabilis can cause pneumonia, particularly in immunocompromised individuals.
• Wound Infections: Proteus mirabilis can infect open wounds, leading to inflammation and delayed healing.

Did you Know ?

Approximately 40% of all UTIs are caused by Proteus mirabilis, making it one of the most common uropathogens.