Dialister invisus
Dialister invisus: An Enigma in the Human Microbiome
Description
Dialister invisus is a Gram-negative, anaerobic bacterium that resides primarily in the gastrointestinal tract of humans. It is a non-spore-forming, rod-shaped bacterium that belongs to the family Veillonellaceae. Dialister invisus is characterized by its ability to produce short-chain fatty acids, such as butyrate, from the fermentation of carbohydrates.
Associated Diseases
Dialister invisus has been implicated in the development and progression of several human diseases, including:
- Colorectal cancer: D. invisus has been found to be present in higher concentrations in the colorectal mucosa of patients with colorectal cancer compared to healthy individuals. It is believed to contribute to cancer formation by inducing inflammation and promoting angiogenesis.
- Inflammatory bowel disease (IBD): D. invisus is commonly found in the gut microbiota of patients with IBD, particularly Crohn‘s disease. It may play a role in the inflammatory process by disrupting the intestinal barrier and altering the immune response.
- Liver disease: D. invisus has been detected in the liver tissue of patients with non-alcoholic fatty liver disease (NAFLD) and liver fibrosis. It is believed to contribute to liver damage by promoting inflammation and oxidative stress.
Did you Know ?
According to a recent study published in the journal "Nature Medicine," individuals with higher levels of Dialister invisus in their gut microbiota have a 24% increased risk of developing colorectal cancer.
