Bacteroides thetaiotaomicron
Bacteroides thetaiotaomicron: A Key Player in Human Health and Disease
Description
Bacteroides thetaiotaomicron is a Gram-negative, rod-shaped bacterium that resides in the human gut microbiome, where it constitutes a significant portion of the microbial community. This bacterium plays a crucial role in human health by contributing to immune function, nutrient metabolism, and the production of essential vitamins.
Associated Diseases
Dysbiosis, an imbalance in the gut microbiome, can lead to various health conditions. Perturbations in B. thetaiotaomicron levels have been linked to several diseases, including:
- Obesity: Reduced levels of B. thetaiotaomicron have been observed in obese individuals, suggesting a role in weight regulation.
- Type 2 diabetes: Alterations in the abundance and activity of B. thetaiotaomicron may contribute to the development of this metabolic disorder.
- Gastrointestinal disorders: Dysbiosis involving B. thetaiotaomicron has been implicated in inflammatory bowel diseases such as Crohn‘s disease and ulcerative colitis.
- Cancer: Certain strains of B. thetaiotaomicron have been found to promote tumor growth in animal models, highlighting a potential association with cancer development.
Did you Know ?
Studies have shown that individuals with higher levels of B. thetaiotaomicron in their gut microbiome tend to have a lower risk of developing obesity. This observation suggests a protective effect against weight gain.
