MGAT4EP
Description
The MGAT4EP (MGAT4 family member E, pseudogene) is a pseudo gene located on chromosome 1.
MGAT4EP, also known as N-acetylglucosaminyltransferase IV epsilon polypeptide, is a glycosyltransferase enzyme. It catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to the core mannose residue of N-glycan precursors in the Golgi apparatus. MGAT4EP is involved in the processing and maturation of N-glycans, which are critical for protein folding, stability, and function.
MGAT4EP, also known as N-acetylglucosaminyltransferase IV epsilon polypeptide, is a glycosyltransferase enzyme that plays a crucial role in the biosynthesis of N-glycans. Specifically, it catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to the core mannose residue of N-glycan precursors in the Golgi apparatus. This step is essential for the proper processing and maturation of N-glycans, which are critical for protein folding, stability, and function. Defects in MGAT4EP have been associated with various disease states, including congenital disorders of glycosylation and neurodevelopmental abnormalities.
MGAT4EP is also known as -.
