MEF2D
Description
The MEF2D (myocyte enhancer factor 2D) is a protein-coding gene located on chromosome 1.
Myocyte-specific enhancer factor 2D is a protein that in humans is encoded by the MEF2D gene.
MEF2D is a transcription activator that binds specifically to the MEF2 element, 5'-YTAATTAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. It mediates cellular functions in skeletal and cardiac muscle development, neuronal differentiation and survival. MEF2D plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. MEF2D also plays a critical role in the regulation of neuronal apoptosis.
MEF2D is also known as -.
