ME3
Description
The ME3 (malic enzyme 3) is a protein-coding gene located on chromosome 11.
ME3 refers to the human gene for NADP-dependent malic enzyme, mitochondrial (NADP-ME), also known as Malic enzyme 3.
ME3 catalyzes the conversion of (S)-malate to pyruvate using NADP+ as a cofactor. This reaction is known as oxidative decarboxylation. ME3 can also reverse this reaction, but it does so with significantly lower efficiency.
ME3 is also known as NADP-ME.
