MDM1
Description
The MDM1 (Mdm1 nuclear protein) is a protein-coding gene located on chromosome 12.
MDM1 is a microtubule-binding protein that plays a crucial role in regulating centriole duplication. It acts as a negative regulator, preventing excessive duplication of these essential cellular structures. MDM1 achieves this by directly interacting with and stabilizing microtubules, which are key components of the cytoskeleton involved in cell division and other vital cellular processes.
MDM1 is also known as -.
Associated Diseases
- retinitis pigmentosa
- retinal degeneration
- X-linked retinal dysplasia
- Leber congenital amaurosis
- Stargardt disease
- choroidal dystrophy, central areolar, 1
- severe early-childhood-onset retinal dystrophy
- Bardet-Biedl syndrome
- progressive bifocal chorioretinal atrophy
