MCM3AP-AS1
Description
The MCM3AP-AS1 (MCM3AP antisense RNA 1) is a ncRNA gene located on chromosome 21.
MCM3AP-AS1 is a long non-coding RNA (lncRNA) located on chromosome 17. It is transcribed from the opposite strand of MCM3AP. Studies have shown that MCM3AP-AS1 is upregulated in several types of cancer, including colorectal cancer, breast cancer, and lung cancer. Its expression levels are associated with tumor progression and poor prognosis in these cancers. MCM3AP-AS1 may play a role in regulating cell proliferation, migration, and invasion, but the specific mechanisms are still being investigated.
MCM3AP-AS1, also known as LINC00668, is a long non-coding RNA (lncRNA) that is located on chromosome 17 and is transcribed from the opposite strand of MCM3AP. It has been found to be upregulated in several cancers, including colorectal cancer, breast cancer, and lung cancer. Studies have shown that MCM3AP-AS1 can promote cell proliferation, migration, and invasion by interacting with various proteins and signaling pathways. For example, it can interact with the miR-205-5p/MCM3AP axis to inhibit cell apoptosis and promote proliferation in colorectal cancer cells. Additionally, MCM3AP-AS1 can function as a sponge for microRNAs, thereby indirectly regulating the expression of target genes. However, the precise molecular mechanisms underlying its involvement in cancer progression are still under investigation. Further research is needed to elucidate its exact roles and potential therapeutic applications.
MCM3AP-AS1 is also known as C21orf85, MCM3AP-AS, MCM3APAS, MCM3APASB, NCRNA00031.
