MAPT-IT1
Description
The MAPT-IT1 (MAPT intronic transcript 1) is a ncRNA gene located on chromosome 17.
MAPT-IT1 is a gene that does not encode a protein but produces a non-coding RNA transcript. This transcript may play a regulatory role in the expression of the nearby MAPT gene, which encodes the microtubule-associated protein tau. Tau is essential for maintaining microtubule stability and axonal transport within neurons. Alterations in MAPT expression have been associated with neurodegenerative diseases such as Alzheimer's disease.
The MAPT-IT1 gene produces a non-coding RNA transcript that may play a role in regulating the expression of the nearby MAPT gene, which encodes the microtubule-associated protein tau. Tau is crucial for microtubule stability and axonal transport in neurons. Dysregulation of MAPT expression has been linked to neurodegenerative disorders like Alzheimer's disease.
MAPT-IT1 is also known as -.
