LTBR

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Description

The LTBR (lymphotoxin beta receptor) is a protein-coding gene located on chromosome 12.

LTBR refers to the human gene Lymphotoxin-beta receptor.

LTBR serves as a receptor for the lymphotoxin complex composed of LTA and LTB, as well as for TNFS14/LIGHT. It triggers apoptosis through interactions with TRAF3 and TRAF5, and may play a crucial role in the development of lymphoid organs.

LTBR is also known as D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3.

Associated Diseases

• upper respiratory tract disorder