LRRTM1
Description
The LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a protein-coding gene located on chromosome 2.
LRRTM1 is a gene found in the brain that produces a protein involved in building connections between nerve cells (neurons). This protein interacts with other proteins (neurexins and neuroligins) to help strengthen these connections. It is specifically active during brain development and shows an interesting pattern of inheritance, being more likely to be active when inherited from the father. While important for brain development, variations in this gene have been linked to an increased chance of being left-handed and a slightly higher risk of mental illnesses like schizophrenia, especially when inherited from the father. LRRTM1 is also essential for processing visual information, as it helps build connections in a part of the brain responsible for visual processing. Mice without this gene have difficulties with complex visual tasks.
LRRTM1 is also known as -.
Associated Diseases
- Alzheimer disease
- substance abuse
- frontotemporal dementia
- childhood disintegrative disorder
- schizophrenia
- Potocki-Lupski syndrome
