LPA
Description
The LPA gene, located on chromosome 1, encodes for the enzyme lysophosphatidic acid acyltransferase (LPAAT), a critical player in lipid metabolism. LPAAT catalyzes the synthesis of lysophosphatidic acid (LPA), a bioactive phospholipid with diverse cellular functions. LPA acts as a signaling molecule, influencing cell growth, migration, survival, and inflammation. The LPA gene exhibits multiple isoforms, each displaying distinct enzymatic activities and tissue expression patterns. Its complex regulation and involvement in various biological processes make it a significant target for research and potential therapeutic interventions.
Associated Diseases
Did you know?
LPA is a unique molecule that can act both as a signaling molecule and a structural component of cell membranes.
