LOXL4


Description

The LOXL4 (lysyl oxidase like 4) is a protein-coding gene located on chromosome 10.

LOXL4 is a member of the lysyl oxidase gene family. This family plays a crucial role in connective tissue formation, with the prototypic member encoding an enzyme that catalyzes the first step in collagen and elastin crosslinking. While the C-terminus of LOXL4 shares a conserved sequence responsible for amine oxidase activity, the N-terminus exhibits less conservation and may contribute to additional functions, such as developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis.

LOXL4 is also known as LOXC.

Associated Diseases



Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.