LOC728673
Title: Loc728673: A Gene Linked to Cancer and Beyond
Description
LOC728673, also known as LINC01488, is a non-coding RNA molecule located on chromosome 1p36.32. It has been found to play a significant role in various biological processes, including cell growth, proliferation, and differentiation. However, abnormal expression of LOC728673 has been associated with several diseases, including cancer.
Associated Diseases
- Cancer: Overexpression of LOC728673 has been linked to the development of various types of cancer, including lung, breast, liver, and gastric cancers. It promotes cancer cell proliferation, invasion, and metastasis by regulating the expression of key genes involved in these processes.
- Neurodegenerative Disorders: LOC728673 has also been implicated in neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases. It modulates the expression of genes involved in neuronal function and survival, contributing to the cognitive and motor impairments observed in these diseases.
- Cardiovascular Diseases: Recent research has linked LOC728673 to cardiovascular diseases, such as atherosclerosis and heart failure. It influences the expression of genes involved in lipid metabolism and vascular function, promoting plaque formation and cardiac dysfunction.
Did you Know ?
According to a study published in the journal "Nature Genetics," elevated LOC728673 expression was found in approximately 60% of lung cancer patients, suggesting its potential as a promising biomarker for cancer diagnosis and prognosis.
