LOC283177
Loc283177: An Intriguing Gene with Diverse Implications
Description
Loc283177 is a gene located on the human chromosome 17. It encodes a protein known as LINC00958, which is a long non-coding RNA (lncRNA). LncRNAs are known to play important roles in regulating gene expression and are involved in various cellular processes.
Associated Diseases
Research suggests that variations in the loc283177 gene may be associated with certain diseases and conditions, including:
- Colorectal cancer: Studies have found that low expression of LINC00958 is associated with increased risk and poor prognosis of colorectal cancer.
- Malignant melanoma: Reduced LINC00958 expression has been linked to tumor growth and progression in malignant melanoma.
- Thyroid cancer: Alterations in loc283177 have been associated with the development of thyroid cancer and may influence tumor behavior.
- Heart failure: Animal studies suggest that LINC00958 may play a role in the development of heart failure by regulating cardiac function.
Did you Know ?
A large-scale study involving over 10,000 individuals revealed that a specific variant in the loc283177 gene was associated with a 15% increased risk of developing colorectal cancer.
