LOC101060321
Understanding Loc101060321: A Comprehensive Overview
Description:
Loc101060321, also known as FAM13B, is a gene located on chromosome 10q21.2. It encodes a protein called Family with Sequence Similarity 13, Member B, which plays a vital role in various cellular processes, including cell growth, differentiation, and metabolism.
Associated Diseases:
- Osteoarthritis (OA): Mutations in the LOC101060321 gene have been linked to an increased risk of developing OA, a degenerative joint disease characterized by pain, stiffness, and reduced mobility.
- Schizophrenia: Studies have suggested an association between variations in LOC101060321 and the development of schizophrenia, a severe mental disorder affecting thought, emotion, and behavior.
- Breast Cancer: Some research has indicated a potential link between LOC101060321 and the risk of breast cancer, although further investigations are needed to confirm this association.
Did you Know ?
Genome-wide association studies (GWAS) have identified a common genetic variant in the LOC101060321 gene that is strongly associated with an increased susceptibility to OA. This variant, known as rs77157999, is present in approximately 15-20% of the general population.
