LINC01105
linc01105: A Long Non-Coding RNA with Intriguing Roles in Human Health
Description
linc01105 is a long non-coding RNA (lncRNA) that is located on chromosome 7p22.1. LncRNAs are RNA molecules that are longer than 200 nucleotides but do not encode proteins. Instead, they play crucial regulatory roles in various cellular processes.
linc01105 has been identified as a key regulator of gene expression and cellular signaling pathways. It interacts with specific proteins to modulate the expression of genes involved in cell growth, proliferation, differentiation, and apoptosis.
Associated Diseases
Dysregulation of linc01105 has been linked to several human diseases, including:
- Cancer: linc01105 is overexpressed in several types of cancer, including breast cancer, lung cancer, and colorectal cancer. Its overexpression promotes cancer cell growth, migration, and invasion.
- Neurodegenerative diseases: linc01105 has been implicated in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. It is involved in neuronal cell death and cognitive impairment.
- Cardiovascular diseases: linc01105 has been associated with cardiovascular diseases such as atherosclerosis and heart failure. It regulates vascular smooth muscle cell growth and inflammation.
- Autoimmune diseases: linc01105 is dysregulated in autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. It modulates immune cell activation and inflammation.
Did you Know ?
According to a recent study, overexpression of linc01105 in breast cancer patients was associated with a 40% higher risk of recurrence and a 30% lower overall survival rate.
