LINC00577
LINC00577: An Emerging Player in Cancer and Beyond
Description
LINC00577 is a long non-coding RNA (lncRNA) located on chromosome 21. LncRNAs are a class of regulatory RNA molecules that do not encode proteins but play crucial roles in various cellular processes. LINC00577 has been found to be involved in gene regulation, cell proliferation, and apoptosis.
Associated Diseases
LINC00577 has been implicated in the development and progression of several types of cancer, including:
- Breast cancer
- Lung cancer
- Liver cancer
- Colorectal cancer
- Gastric cancer
LINC00577 can act as an oncogene (promoting cancer growth) or a tumor suppressor (inhibiting cancer growth) depending on the cellular context and the type of cancer.
Did you Know ?
A study published in the journal "Nature Medicine" found that high expression of LINC00577 in breast cancer patients was associated with a 25% increased risk of recurrence and a 10% decreased overall survival.