LINC00271
linc00271: A Long Non-Coding RNA with Intriguing Roles in Disease and Health
Description
linc00271 is a long non-coding RNA (lncRNA) that plays a vital role in various biological processes. It is located on chromosome 20q11.21 in the human genome and has a length of approximately 3,500 nucleotides. As a non-coding RNA, linc00271 does not code for proteins but instead regulates gene expression through complex mechanisms.
Associated Diseases
Research has linked linc00271 to the development and progression of several diseases, including:
- Cancer: Studies have shown that linc00271 overexpression is associated with increased tumor growth, metastasis, and decreased patient survival in cancers such as lung, breast, and colorectal cancers.
- Cardiovascular diseases: Alterations in linc00271 expression have been implicated in cardiac hypertrophy, fibrosis, and heart failure.
- Metabolic disorders: Linc00271 dysregulation has been linked to obesity, insulin resistance, and type 2 diabetes.
- Neurodegenerative diseases: Emerging evidence suggests that linc00271 plays a role in the development of Alzheimer's disease and Parkinson's disease.
Did you Know ?
Studies estimate that over 40% of the human genome is transcribed into lncRNAs, including linc00271. This highlights the significant role that non-coding RNAs play in cellular and physiological functions.
