LHX8
Description
The LHX8 (LIM homeobox 8) is a protein-coding gene located on chromosome 1.
LHX8 acts as a transcription factor, playing a critical role in guiding the development of specific types of neurons and mesenchymal cells.
LHX8 is also known as LHX7.
Associated Diseases
- 46,XX testicular disorder of sex development
- 46,XY complete gonadal dysgenesis
- Perrault syndrome
- 46,XX ovotesticular disorder of sex development
- lethal omphalocele-cleft palate syndrome
- partial androgen insensitivity syndrome
- ring chromosome Y
- Kallmann syndrome
- partial chromosome Y deletion
- male infertility with teratozoospermia due to single gene mutation
- spermatogenic failures 50
- spermatogenic failure 25
- aromatase deficiency
