LEPROTL1
Description
The LEPROTL1 (leptin receptor overlapping transcript like 1) is a protein-coding gene located on chromosome 8.
LEPROTL1 negatively regulates the expression of growth hormone (GH) receptors on the surface of liver cells. This regulation might be involved in the liver's resistance to GH during times when nutrients are scarce.
LEPROTL1 is also known as HSPC112, Vps55, my047.
Associated Diseases
- skin basal cell carcinoma
- skin squamous cell carcinoma
- carcinoma of liver and intrahepatic biliary tract