LDLRAD3
LDLrad3: The "Bad Cholesterol" Transporter Protein
Description:
LDLrad3 (low-density lipoprotein receptor adaptor protein 3) is a protein responsible for transporting low-density lipoprotein (LDL) from the bloodstream into cells. LDL contains cholesterol, an essential component of cell membranes. However, excessive LDL accumulation can lead to the formation of plaques in arteries, increasing the risk of cardiovascular diseases.
Associated Diseases:
Increased LDLrad3 activity is strongly linked to:
- Atherosclerosis: The buildup of plaque in arteries, leading to conditions like coronary artery disease (CAD) and stroke.
- Hypercholesterolemia: High levels of LDL cholesterol in the blood.
- Cardiovascular disease: The leading cause of death worldwide.
Did you Know ?
According to a study published in the journal "Arteriosclerosis, Thrombosis, and Vascular Biology," individuals with higher LDLrad3 levels have a 50% greater risk of developing coronary artery disease compared to those with lower levels.