LAD1

Description

The LAD1 (ladinin 1) is a protein-coding gene located on chromosome 1.

Ladinin-1 is a protein encoded by the LAD1 gene in humans. It may act as an anchoring filament, contributing to the stability of the basement membrane. This protein may play a role in maintaining the connection between epithelial layers and the underlying mesenchyme.

LAD1 encodes a protein that functions as an anchoring filament, a structural component of the basement membrane zone.

LAD1 is also known as LadA.

Associated Diseases

• cancer
• breast cancer
• generalized junctional epidermolysis bullosa non-Herlitz type
• skin basal cell carcinoma
• severe combined immunodeficiency