KRTAP27-1
Description
The KRTAP27-1 (keratin associated protein 27-1) is a protein-coding gene located on chromosome 21.
KRTAP27-1 is involved in the formation of a rigid and resistant hair shaft within the hair cortex. It interacts with hair keratin intermediate filaments, forming an interfilamentous matrix. This matrix is essential for hair strength and structure, achieved through extensive disulfide bond cross-linking between KRTAP27-1 and hair keratins, facilitated by the abundance of cysteine residues in both.
KRTAP27-1 is also known as -.