KRTAP26-1
Description
The KRTAP26-1 (keratin associated protein 26-1) is a protein-coding gene located on chromosome 21.
KRTAP26-1 plays a crucial role in the hair cortex by forming an interfilamentous matrix that surrounds hair keratin intermediate filaments. This matrix is essential for the formation of a rigid and resistant hair shaft. KRTAP26-1 achieves this through extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins, including KRTAP26-1, are categorized as high-sulfur and high-glycine-tyrosine keratins.
KRTAP26-1 is also known as -.
