KRTAP10-12


Description

The KRTAP10-12 (keratin associated protein 10-12) is a protein-coding gene located on chromosome 21.

KRTAP10-12, a hair keratin-associated protein, plays a crucial role in the structural integrity of hair. Within the hair cortex, KRTAP10-12 forms part of an interfilamentous matrix that surrounds keratin intermediate filaments. This matrix is essential for providing the hair shaft with its rigidity and resistance. KRTAP10-12 contributes to these properties through extensive disulfide bond cross-linking with cysteine residues in hair keratins.

KRTAP10-12 is also known as KAP10.12, KRTAP18-12, KRTAP18.12.

Associated Diseases



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