KRTAP10-11
Description
The KRTAP10-11 (keratin associated protein 10-11) is a protein-coding gene located on chromosome 21.
KRTAP10-11 is a keratin-associated protein found in the hair cortex. It plays a crucial role in forming the hair shaft's rigid structure by interacting with hair keratin intermediate filaments. This interaction involves extensive disulfide bond cross-linking between KRTAP10-11 and hair keratins, which contain abundant cysteine residues. This protein belongs to the group of high-sulfur keratin-associated proteins, essential for hair shaft integrity.
KRTAP10-11 is also known as KAP10.11, KAP10.9, KAP18-9, KAP18.11, KRTAP10-9, KRTAP10.9, KRTAP18-11, KRTAP18-9, KRTAP18.11, KRTAP18.9.
Associated Diseases
- ovarian cancer
- thyroid gland adenocarcinoma
- esophageal cancer
- myoepithelial tumor
- schizophrenia 15
- Phelan-McDermid syndrome
- Potocki-Lupski syndrome
