KLRC3

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Description

The KLRC3 (killer cell lectin like receptor C3) is a protein-coding gene located on chromosome 12.

KLRC3 acts as a receptor that enables natural killer (NK) cells and certain cytotoxic T cells to recognize HLA-E molecules, which are a type of MHC class I protein.

KLRC3 is also known as NKG2-E, NKG2E.

Associated Diseases

• glioblastoma
• histidinemia
• hypouricemia, renal, 2
• type 1 diabetes mellitus
• Wiskott-Aldrich syndrome