KLK13

Description

The KLK13 (kallikrein related peptidase 13) is a protein-coding gene located on chromosome 19.

Kallikrein-13 is a protein encoded by the KLK13 gene in humans. Kallikreins are a group of serine proteases with various roles in the body. While the exact function of Kallikrein-13 is not fully understood, it is thought to be involved in protecting the upper digestive system, breaking down extracellular matrix, tissue remodeling, and male reproductive functions. This gene is part of a cluster of 15 kallikrein genes on chromosome 19. Its expression is controlled by steroid hormones and might be a marker for breast cancer. An additional version of this gene's instructions has been found, but its complete sequence is unknown. Kallikrein-13 acts as a priming protease during infection by the human coronavirus HKU1. Many kallikreins are linked to cancer development, and some have potential as markers for cancer and other diseases.

KLK13 is also known as KLK-L4, KLKL4.

Associated Diseases


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