KIF4B
Description
The KIF4B (kinesin family member 4B) is a protein-coding gene located on chromosome 5.
KIF4B is a human protein encoded by the KIF4B gene. It belongs to the kinesin family of motor proteins. KIF4B and its closely related protein KIF4A are vital for regulating anaphase spindle dynamics during mitosis.
KIF4B is an iron-sulfur (Fe-S) cluster binding motor protein involved in chromosome segregation during mitosis. It translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, crucial for forming the organized central spindle midzone, midbody, and successful cytokinesis. It may also contribute to mitotic chromosomal positioning and bipolar spindle stabilization.
KIF4B is also known as -.
