KIF25
Description
The KIF25 (kinesin family member 25) is a protein-coding gene located on chromosome 6.
KIF25, also known as kinesin-14, is a human protein encoded by the KIF25 gene. It is part of the kinesin family of motor proteins. KIF25 is a minus-end directed microtubule motor protein, and its activity delays the separation of chromosomes during mitosis.
KIF25 is a motor protein that moves along microtubules towards the minus end. It acts as a negative regulator of centrosome separation, preventing premature separation during interphase. It is also important for maintaining a centered nucleus, which ensures that the spindle is properly oriented at the start of mitosis. KIF25 may also play a role in regulating autophagy, specifically in response to amino acid starvation.
KIF25 is also known as KNSL3.
Associated Diseases
- lysosomal storage disease
- Alzheimer disease
- multiple sclerosis
- Parkinson disease
- ovarian cancer
- low grade glioma
