KIAA2012
Description
The KIAA2012 (KIAA2012) is a protein-coding gene located on chromosome 2.
KIAA2012 is a protein which, in humans, is encoded by the KIAA2012 gene. KIAA2012 is expressed at very low levels throughout the body, but it is primarily expressed in the ovary, lungs, and brain.
== Gene ==
KIAA2012 is located on the positive sense strand at position 2q33.1. KIAA2012 has 24 exons, and it spans 131,934 bases including introns. No aliases or common names are used in addition to KIAA2012.
=== Gene level regulation === Within the promoter region of KIAA2012, there is a highly conserved transcription factor binding site that has no common SNPs. The RFX transcription factors, more specifically RFX1-6, bind to this highly conserved region and regulates cellular specialization and differentiation. The image below shows the promoter region of KIAA2012 with the highly conserved RFX1-6 binding site.
== mRNA == KIAA2012 is expressed differentially in the body at low levels. Of this overall low expression, KIAA2012 is expressed most highly in the brain, lungs, and ovary.
KIAA2012 is also known as -.
