KCNT2
Description
The KCNT2 (potassium sodium-activated channel subfamily T member 2) is a protein-coding gene located on chromosome 1.
KCNT2 (Potassium channel subfamily T, member 2), also known as KNa protein, is an outwardly rectifying potassium channel activated by internal increases in sodium or chloride ions. It is also referred to as the Slick channel (sequence like an intermediate calcium channel).
KCNT2 is an outward rectifying potassium channel that generates rapidly activating outward rectifier K(+) currents. It is activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and inhalation anesthetics like isoflurane. It is also inhibited upon stimulation of G-protein coupled receptors such as CHRM1 and GRM1.
KCNT2 is also known as DEE57, EIEE57, KCa4.2, SLICK, SLO2.1.
