KCNJ8
Description
The KCNJ8 (potassium inwardly rectifying channel subfamily J member 8) is a protein-coding gene located on chromosome 12.
KCNJ8, also known as Kir6.1, is a human gene encoding the Kir6.1 protein, an inward-rectifier type potassium channel. Mutations in KCNJ8 have been linked to early repolarization syndrome and cardiac arrest. Kir6.1, which is controlled by G-proteins, is present in many mammalian cells and plays a role in various physiological responses. It allows potassium to flow more easily into a cell than out.
KCNJ8 is also known as KIR6.1, uKATP-1.
