KCNJ4
Description
The KCNJ4 (potassium inwardly rectifying channel subfamily J member 4) is a protein-coding gene located on chromosome 22.
KCNJ4, or Kir2.3, is a human gene encoding an integral membrane protein involved in electrical signaling in the nervous system. It belongs to the inward rectifier potassium channel family, facilitating potassium flow into cells. This protein has a smaller unitary conductance than other family members, contributing to the excitability of muscle cells and neurons. It interacts with various proteins like CASK, DLG1, DLG4, LIN7B, and LIN7C, playing a role in cell function.
KCNJ4 is also known as HIR, HIRK2, HRK1, IRK-3, IRK3, Kir2.3.
