KCNJ11

The KCNJ11 gene, crucial for insulin secretion, influences diabetes susceptibility and treatment response.

Associated Diseases

Neonatal Diabetes, Type 2 Diabetes, Hyperinsulinemic hypoglycemic familial- 2, Maturity-onset diabetes of the young, type 13

Did you know

The KCNJ11 gene encodes a potassium channel crucial for regulating insulin secretion in the pancreas. This channel plays a pivotal role in controlling blood sugar levels by facilitating the release of insulin from pancreatic beta cells. Mutations in the KCNJ11 gene can disrupt this process, leading to various forms of diabetes, including neonatal diabetes and maturity-onset diabetes of the young (MODY). Understanding KCNJ11 gene function is vital for diagnosing and managing these diabetes subtypes, as well as for developing targeted therapies to improve insulin secretion and blood glucose control in affected individuals.