KCNC4


Description

The KCNC4 (potassium voltage-gated channel subfamily C member 4) is a protein-coding gene located on chromosome 1.

KCNC4, also known as Kv3.4, is a human gene that encodes a protein belonging to the delayed rectifier class of potassium channel proteins. This protein is an integral membrane protein that facilitates the voltage-dependent movement of potassium ions across excitable membranes. It creates a transient current that may be important for neuronal excitability. The gene is part of the Shaw subfamily, which is related to the Shaker gene family in Drosophila. Several different isoforms of this protein have been identified.

This protein controls the flow of potassium ions across the membranes of excitable cells, such as neurons. It does this by opening or closing a channel in the membrane in response to changes in voltage. The channel is selective for potassium ions, allowing them to pass through according to their electrochemical gradient.

KCNC4 is also known as C1orf30, HKSHIIIC, KSHIIIC, KV3.4.

Associated Diseases



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