JSRP1
Description
The JSRP1 (junctional sarcoplasmic reticulum protein 1) is a protein-coding gene located on chromosome 19.
JSRP1 plays a crucial role in skeletal muscle excitation-contraction coupling (EC), a process that converts electrical signals into chemical signals. It likely functions as a regulator of the voltage-sensitive calcium channel CACNA1S. During EC, an electrical signal (depolarization of the plasma membrane) triggers the opening of ryanodine receptor calcium release channels, resulting in a calcium gradient. JSRP1 may influence the location and activity of CACNA1S within the cell membrane.
JSRP1 is also known as JP-45, JP45.
