JMJD7-PLA2G4B
Description
The JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough) is a protein-coding gene located on chromosome 15.
JMJD7-PLA2G4B is a chimeric gene fusion protein formed by a chromosomal rearrangement that combines parts of the JMJD7 and PLA2G4B genes. This fusion is associated with certain types of cancer, particularly leukemia, and has been implicated in disease progression. The fusion protein is thought to disrupt normal cellular functions by altering gene expression and signaling pathways, potentially contributing to uncontrolled cell growth.
The JMJD7-PLA2G4B fusion protein is a chimeric protein resulting from a chromosomal rearrangement that combines portions of the JMJD7 and PLA2G4B genes. This fusion is associated with certain types of cancer, particularly leukemia, and has been found to contribute to disease progression. While the exact mechanisms are still being studied, the fusion protein is thought to disrupt normal cellular processes by altering gene expression and cellular signaling pathways, ultimately promoting uncontrolled cell growth.
JMJD7-PLA2G4B is also known as HsT16992, cPLA2-beta.
