JMJD4
Description
The JMJD4 (jumonji domain containing 4) is a protein-coding gene located on chromosome 1.
JMJD4 is an enzyme that catalyzes the hydroxylation of lysine 63 on ETF1, a protein involved in electron transport. This hydroxylation reaction requires 2-oxoglutarate and iron as cofactors and promotes the efficient termination of translation by ETF1.
JMJD4 is also known as -.
Associated Diseases
- nonpapillary renal cell carcinoma
- hemoglobin D disease
- amelogenesis imperfecta
- dentin dysplasia type I
- hemoglobin E-beta-thalassemia syndrome
- hemoglobin E disease
- dentinogenesis imperfecta
- cancer
