ISL2
Description
The ISL2 (ISL LIM homeobox 2) is a protein-coding gene located on chromosome 15.
ISL2 is a transcription factor that plays a crucial role in the development of motor neurons. It helps to define different subtypes of motor neurons, which then organize into distinct columns within the spinal cord. ISL2 also guides these motor neurons to select specific pathways for their axons.
ISL2 is also known as -.
Associated Diseases
- amyotrophic lateral sclerosis
- hereditary neuropathy with liability to pressure palsies
- diarrhea-vomiting due to trehalase deficiency
- congenital sucrase-isomaltase deficiency
- lethal congenital contracture syndrome 3
