INSL6

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Title: INSULIN-LIKE GROWTH FACTOR 6 (INSL6)

Description:

Insulin-like growth factor 6 (INSL6) is a protein hormone that belongs to the insulin superfamily. It is primarily produced by Leydig cells in the testes and is involved in regulating fertility and reproductive development.

Associated Diseases:

Mutations in the INSL6 gene are associated with several disorders, including:

• Cryptorchidism (undescended testes)
• Leydig cell aplasia (absence of Leydig cells)
• Kallmann syndrome (a rare genetic disorder characterized by delayed puberty and infertility)

Did you Know ?

Approximately 1 in 500 men worldwide are affected by cryptorchidism, which is often associated with INSL6 mutations.