TEX15
Description
The TEX15 gene plays a pivotal role in male fertility by encoding a protein essential for proper meiotic cell division, a specialized type of cell division that produces sperm cells. This protein, TEX15, localizes to the synaptonemal complex, a protein structure that facilitates chromosome pairing and recombination during meiosis. Disruptions in TEX15 function can lead to impaired spermatogenesis and male infertility. Understanding the intricacies of TEX15 and its role in meiosis is crucial for developing diagnostic tools and potential therapeutic strategies for male infertility.
Associated Diseases
- Male infertility
- Azoospermia (absence of sperm in semen)
- Oligospermia (low sperm count)
- Teratozoospermia (abnormal sperm morphology)
Did you know?
Mutations in the TEX15 gene are associated with a rare genetic disorder known as TEX15 syndrome, characterized by male infertility, developmental abnormalities, and intellectual disability.
