HTRA1
Description
The HTA1 gene, located on chromosome 16, encodes for histone H1.0, a crucial component of chromatin structure. Histones are proteins that package and organize DNA within the nucleus, regulating gene expression and DNA replication. HTA1‘s role in maintaining genome stability and cell division highlights its significance in human health.
Associated Diseases
- Cancer: Aberrant HTA1 expression is linked to various cancers, including breast, colorectal, and lung cancer.
- Neurological Disorders: HTA1 dysregulation is associated with neurodevelopmental disorders and neurodegenerative diseases like Alzheimer‘s disease.
- Cardiovascular Diseases: Studies suggest a potential role of HTA1 in cardiovascular health and disease development.
Did you know?
The HTA1 gene is highly conserved across different species, indicating its fundamental role in cellular processes.
