HOXC4

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Description

The HOXC4 (homeobox C4) is a protein-coding gene located on chromosome 12.

HOXC4 is a homeobox gene that encodes a transcription factor involved in the development of multicellular organisms. HOXC4 is part of the HOXC gene cluster located on chromosome 12. It is expressed in a variety of tissues and plays a role in morphogenesis. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Two alternatively spliced variants of HOXC4 exist, both encoding the same protein. HOXC4 has been shown to interact with Ku70.

HOXC4 is also known as HOX3, HOX3E, cp19.

Associated Diseases