HOXB2
Description
The HOXB2 (homeobox B2) is a protein-coding gene located on chromosome 17.
HOXB2 is a human gene that encodes a nuclear protein with a homeobox DNA-binding domain. It belongs to the Antp homeobox family and is part of a cluster of homeobox B genes on chromosome 17. This protein acts as a transcription factor involved in development, with its increased expression linked to pancreatic cancer.
HOXB2 is a sequence-specific transcription factor involved in a developmental regulatory system that determines the positional identity of cells along the anterior-posterior axis.
HOXB2 is also known as HOX2, HOX2H, Hox-2.8, K8.
