HOXA11-AS
Description
The HOXA11-AS (HOXA11 antisense RNA) is a ncRNA gene located on chromosome 7.
HOXA11-AS is a long non-coding RNA (lncRNA) located on chromosome 7, in the vicinity of the HOXA gene cluster. It is a transcribed RNA molecule that does not encode for a protein but plays an important role in regulating gene expression. HOXA11-AS has been shown to interact with various cellular components, including microRNAs (miRNAs), proteins, and DNA, suggesting its involvement in multiple cellular processes.
HOXA11-AS is a long non-coding RNA (lncRNA) that plays a crucial role in regulating the expression of genes involved in various cellular processes, including cell proliferation, differentiation, and development. It acts as a molecular sponge, sequestering microRNAs (miRNAs) and thereby preventing them from silencing their target mRNAs. This leads to an increase in the expression of genes targeted by those miRNAs. Additionally, HOXA11-AS has been shown to interact with proteins involved in chromatin remodeling, suggesting a potential role in regulating gene transcription. This lncRNA exhibits tissue-specific expression patterns, suggesting its involvement in diverse biological processes. Its dysregulation has been implicated in various diseases, including cancer and developmental disorders.
HOXA11-AS is also known as HOXA-AS5, HOXA11-AS1, HOXA11AS, HOXA11S, LncHOXA11, NCRNA00076.
