HNRNPU-AS1

hnrnpul-as1: A Long Non-Coding RNA with Intriguing Roles in Disease

Description

hnrnpu-as1 is a long non-coding RNA (lncRNA), a type of RNA molecule that does not code for proteins. It is located on chromosome 14q11.2 and plays a crucial role in regulating gene expression.

Associated Diseases

Dysregulation of hnrnpul-as1 has been linked to several diseases:

  • Alzheimer's Disease: hnrnpul-as1 levels are decreased in Alzheimer's disease and may contribute to cognitive impairment.
  • Pancreatic Cancer: High levels of hnrnpul-as1 promote tumor growth and metastasis in pancreatic cancer.
  • Hepatocellular Carcinoma: Overexpression of hnrnpul-as1 inhibits apoptosis and promotes cell proliferation in hepatocellular carcinoma.
  • Systemic Lupus Erythematosus (SLE): hnrnpul-as1 is involved in the pathogenesis of SLE by regulating immune responses.

Did you Know ?

Studies have shown that approximately 50% of Alzheimer's disease patients have reduced levels of hnrnpul-as1, suggesting its potential role as a biomarker for the disease.


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Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.